Publications by the researcher in collaboration with FRANCISCO JAVIER LACADENA GARCÍA-GALLO (54)

2024

  1. Combination of T cell-redirecting strategies with a bispecific antibody blocking TGF-β and PD-L1 enhances antitumor responses

    OncoImmunology, Vol. 13, Núm. 1

2023

  1. A New Optimized Version of a Colorectal Cancer-Targeted Immunotoxin Based on a Non-Immunogenic Variant of the Ribotoxin α-Sarcin

    Cancers, Vol. 15, Núm. 4

  2. Nanobody-Based EGFR-Targeting Immunotoxins for Colorectal Cancer Treatment

    Biomolecules, Vol. 13, Núm. 7

2022

  1. Trispecific T-cell engagers for dual tumor-targeting of colorectal cancer

    Oncoimmunology, Vol. 11, Núm. 1, pp. 2034355

2019

  1. A novel Carcinoembryonic Antigen (CEA)-Targeted Trimeric Immunotoxin shows significantly enhanced Antitumor Activity in Human Colorectal Cancer Xenografts

    Scientific Reports, Vol. 9, Núm. 1

  2. Inclusion of a Furin Cleavage Site Enhances Antitumor Efficacy against Colorectal Cancer Cells of Ribotoxin α-Sarcin- or RNase T1-Based Immunotoxins

    Toxins, Vol. 11, Núm. 10

2017

  1. Fungal ribotoxins: A review of potential biotechnological applications

    Toxins, Vol. 9, Núm. 2

  2. Minimized natural versions of fungal ribotoxins show improved active site plasticity

    Archives of Biochemistry and Biophysics, Vol. 619, pp. 45-53

2016

  1. Involvement of loop 5 lysine residues and the N-terminal β-hairpin of the ribotoxin hirsutellin A on its insecticidal activity

    Biological Chemistry, Vol. 397, Núm. 2, pp. 135-145

  2. Synergistic action of actinoporin isoforms from the same sea anemone species assembled into functionally active heteropores

    Journal of Biological Chemistry, Vol. 291, Núm. 27, pp. 14109-14119

2015

  1. Efficient in vivo antitumor effect of an immunotoxin based on ribotoxin α-sarcin in nude mice bearing human colorectal cancer xenografts

    SpringerPlus, Vol. 4, Núm. 1

  2. Involvement of loops 2 and 3 of α-sarcin on its ribotoxic activity

    Toxicon, Vol. 96, pp. 1-9

  3. Preparation of an engineered safer immunotoxin against colon carcinoma based on the ribotoxin hirsutellin A

    FEBS Journal, Vol. 282, Núm. 11, pp. 2131-2141

  4. α-sarcin and RNase T1 based immunoconjugates: The role of intracellular trafficking in cytotoxic efficiency

    FEBS Journal, Vol. 282, Núm. 4, pp. 673-684

2013

  1. Hirsutellin A: A paradigmatic example of the insecticidal function of fungal ribotoxins

    Insects, Vol. 4, Núm. 3, pp. 339-356

2012

  1. A non-cytotoxic but ribonucleolytically specific ribotoxin variant: Implication of tryptophan residues in the cytotoxicity of hirsutellin A

    Biological Chemistry, Vol. 393, Núm. 6, pp. 449-456

  2. Implication of an Asp residue in the ribonucleolytic activity of hirsutellin A reveals new electrostatic interactions at the active site of ribotoxins

    Biochimie, Vol. 94, Núm. 2, pp. 427-433

  3. Production and characterization of a colon cancer-specific immunotoxin based on the fungal ribotoxin α-sarcin

    Protein Engineering, Design and Selection, Vol. 25, Núm. 8, pp. 425-435

  4. Production and characterization of scFvA33T1, an immunoRNase targeting colon cancer cells

    FEBS Journal, Vol. 279, Núm. 17, pp. 3022-3032

2008

  1. The insecticidal protein hirsutellin A from the mite fungal pathogen Hirsutella thompsonii is a ribotoxin

    Proteins: Structure, Function and Genetics, Vol. 72, Núm. 1, pp. 217-228