Farmacia
Fakultät
Instituto de Química Orgánica General
Madrid, EspañaPublikationen in Zusammenarbeit mit Forschern von Instituto de Química Orgánica General (405)
2024
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Chitosan-based oral hydrogel formulations of β-galactosidase to improve enzyme supplementation therapy for lactose intolerance
International Journal of Biological Macromolecules, Vol. 255
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Design and Synthesis of Multi-Functional Ligands through Hantzsch Reaction: Targeting Ca2+ Channels, Activating Nrf2 and Possessing Cathepsin S Inhibitory, and Antioxidant Properties
Pharmaceutics, Vol. 16, Núm. 1
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Synthesis and Biological Evaluation of New Benzochromenopyrimidines for the Therapy of Colon and Lung Cancer
ChemistrySelect, Vol. 9, Núm. 2
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Synthesis, antioxidant and neuroprotective analysis of diversely functionalized α-aryl-N-alkyl nitrones as potential agents for ischemic stroke therapy
European Journal of Medicinal Chemistry, Vol. 266
2023
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8-Hydroxyquinolylnitrones as multifunctional ligands for the therapy of neurodegenerative diseases
Acta Pharmaceutica Sinica B, Vol. 13, Núm. 5, pp. 2152-2175
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Biginelli Reaction Synthesis of Novel Multitarget-Directed Ligands with Ca2+ Channel Blocking Ability, Cholinesterase Inhibition, Antioxidant Capacity, and Nrf2 Activation
Molecules, Vol. 28, Núm. 1
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Design, Synthesis, in Silico and Biological Evaluation of Novel 4-Aminopyrimidine-5-carbonitriles
ChemistrySelect, Vol. 8, Núm. 31
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Exploring the Potential of Sulfonamide-Dihydropyridine Hybrids as Multitargeted Ligands for Alzheimer’s Disease Treatment
International Journal of Molecular Sciences, Vol. 24, Núm. 11
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Fast and Sustained Axonal Growth by BDNF Released from Chitosan Microspheres
Marine Drugs, Vol. 21, Núm. 2
2022
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Benzochromenopyrimidines: Synthesis, Antiproliferative Activity against Colorectal Cancer and Physicochemical Properties
Molecules, Vol. 27, Núm. 22
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Evaluation of PCDD/Fs, PCBs and PBDEs in two penguin species from Antarctica
Chemosphere, Vol. 286
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Improving the Efficacy of Quinolylnitrones for Ischemic Stroke Therapy, QN4 and QN15 as New Neuroprotective Agents after Oxygen–Glucose Deprivation/Reoxygenation-Induced Neuronal Injury
Pharmaceuticals, Vol. 15, Núm. 11
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N-Hydroxy-N-Propargylamide Derivatives of Ferulic Acid: Inhibitors of Cholinesterases and Monoamine Oxidases
Molecules, Vol. 27, Núm. 21
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Postischemic Neuroprotection of Aminoethoxydiphenyl Borate Associates Shortening of Peri-Infarct Depolarizations
International Journal of Molecular Sciences, Vol. 23, Núm. 13
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Preclinical Characterization of Antioxidant Quinolyl Nitrone QN23 as a New Candidate for the Treatment of Ischemic Stroke
Antioxidants, Vol. 11, Núm. 6
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Privileged multi-target directed propargyl-tacrines combining cholinesterase and monoamine oxidase inhibition activities
Journal of Enzyme Inhibition and Medicinal Chemistry, Vol. 37, Núm. 1, pp. 2605-2620
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Synthesis and Pharmacological Evaluation of New N-Sulfonylureas as NLRP3 Inflammasome Inhibitors: Identification of a Hit Compound to Treat Gout
Journal of Medicinal Chemistry, Vol. 65, Núm. 8, pp. 6250-6260
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The Chemotype of Chromanones as a Privileged Scaffold for Multineurotarget Anti-Alzheimer Agents
ACS Pharmacology and Translational Science, Vol. 5, Núm. 11, pp. 1097-1108
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The Synthesis of 3-Nitrooxypropanol, a Methane Mitigant for Sustainable Farming with Environmental Impact: A Review
Synthesis (Germany), Vol. 55, Núm. 14, pp. 2109-2117
2021
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(±)- BIGI-3h: Pentatarget-Directed Ligand combining Cholinesterase, Monoamine Oxidase, and Glycogen Synthase Kinase 3β Inhibition with Calcium Channel Antagonism and Antiaggregating Properties for Alzheimer's Disease
ACS Chemical Neuroscience, Vol. 12, Núm. 8, pp. 1328-1342