Publicaciones en colaboración con investigadores/as de Instituto de Química Médica (20)

2023

  1. Nutrition Security of Hemp for Human Consumption

    Sustainable Food Science - A Comprehensive Approach: Volumes 1-4 (Elsevier), pp. V3-60-V3-88

2022

  1. IQM-PC332, a Novel DREAM Ligand with Antinociceptive Effect on Peripheral Nerve Injury-Induced Pain

    International Journal of Molecular Sciences, Vol. 23, Núm. 4

  2. β-Lactam TRPM8 Antagonist RGM8-51 Displays Antinociceptive Activity in Different Animal Models

    International Journal of Molecular Sciences, Vol. 23, Núm. 5

2021

  1. Changes in fatty acid dietary profile affect the brain–gut axis functions of healthy young adult rats in a sex-dependent manner

    Nutrients, Vol. 13, Núm. 6

  2. Effects of coffee and its components on the gastrointestinal tract and the brain–gut axis

    Nutrients, Vol. 13, Núm. 1, pp. 1-34

2020

  1. Cannabidiol and other non-psychoactive cannabinoids for prevention and treatment of gastrointestinal disorders: Useful nutraceuticals?

    International Journal of Molecular Sciences, Vol. 21, Núm. 9

2019

  1. Discovery and Pharmacological Studies of 4-Hydroxyphenyl-Derived Phosphonium Salts Active in a Mouse Model of Visceral Leishmaniasis

    Journal of Medicinal Chemistry, Vol. 62, Núm. 23, pp. 10664-10675

  2. Identification of IQM-266, a novel DREAM ligand that modulates KV4 currents

    Frontiers in Molecular Neuroscience, Vol. 12

  3. New flavonoid–N,N-dibenzyl(N-methyl)amine hybrids: Multi-target-directed agents for Alzheimer´s disease endowed with neurogenic properties

    Journal of Enzyme Inhibition and Medicinal Chemistry, Vol. 34, Núm. 1, pp. 712-727

2018

  1. Neurogenic and neuroprotective donepezil-flavonoid hybrids with sigma-1 affinity and inhibition of key enzymes in Alzheimer's disease

    European Journal of Medicinal Chemistry, Vol. 156, pp. 534-553

2016

  1. New cinnamic - N-benzylpiperidine and cinnamic - N,N-dibenzyl(N-methyl)amine hybrids as Alzheimer-directed multitarget drugs with antioxidant, cholinergic, neuroprotective and neurogenic properties

    European Journal of Medicinal Chemistry, Vol. 121, pp. 376-386

2015

  1. Novel tacrine-grafted ugi adducts as multipotent anti-alzheimer drugs: A synthetic renewal in tacrine-ferulic acid hybrids

    ChemMedChem, Vol. 10, Núm. 3, pp. 523-539

  2. Selective, nontoxic CB2 cannabinoid o-quinone with in vivo activity against triple-negative breast cancer

    Journal of Medicinal Chemistry, Vol. 58, Núm. 5, pp. 2256-2264

2014

  1. Dibenzo[1,4,5]thiadiazepine: A hardly-known heterocyclic system with neuroprotective properties of potential usefulness in the treatment of neurodegenerative diseases

    European Journal of Medicinal Chemistry, Vol. 81, pp. 350-358

  2. ITH12410/SC058: A new neuroprotective compound with potential in the treatment of Alzheimer's disease

    ACS Chemical Neuroscience, Vol. 5, Núm. 9, pp. 770-775

  3. New melatonin- N, N -dibenzyl(N -methyl)amine hybrids: Potent neurogenic agents with antioxidant, cholinergic, and neuroprotective properties as innovative drugs for alzheimers disease

    Journal of Medicinal Chemistry, Vol. 57, Núm. 9, pp. 3773-3785

2013

  1. Novel multitarget ligand ITH33/IQM9.21 provides neuroprotection in in vitro and in vivo models related to brain ischemia

    Neuropharmacology, Vol. 67, pp. 403-411

  2. PP2A ligand ITH12246 protects against memory impairment and focal cerebral ischemia in mice

    ACS Chemical Neuroscience, Vol. 4, Núm. 9, pp. 1267-1277

2012

  1. Synthesis, biological assessment, and molecular modeling of racemic 7-aryl-9,10,11,12-tetrahydro-7H-benzo[7,8]chromeno[2,3-b]quinolin-8-amines as potential drugs for the treatment of Alzheimer's disease

    European Journal of Medicinal Chemistry, Vol. 54, pp. 750-763

2011

  1. N-Acylaminophenothiazines: Neuroprotective agents displaying multifunctional activities for a potential treatment of Alzheimer's disease

    European Journal of Medicinal Chemistry, Vol. 46, Núm. 6, pp. 2224-2235