Publicaciones en colaboración con investigadores/as de Centro Nacional de Investigaciones Oncológicas (68)

2024

  1. CRISPR/Cas9 screenings unearth protein arginine methyltransferase 7 as a novel essential gene in prostate cancer metastasis

    Cancer Letters, Vol. 588

  2. MCJ: A mitochondrial target for cardiac intervention in pulmonary hypertension

    Science advances, Vol. 10, Núm. 3, pp. eadk6524

2022

  1. A mouse model for Li-Fraumeni-Like Syndrome with cardiac angiosarcomas associated to POT1 mutations

    PLoS Genetics, Vol. 18, Núm. 6

  2. Alkylating Agent-Induced Toxicity and Melatonin-Based Therapies

    Frontiers in Pharmacology, Vol. 13

  3. Consequences of telomere dysfunction in fibroblasts, club and basal cells for lung fibrosis development

    Nature Communications, Vol. 13, Núm. 1

  4. Tunable gold nanorod/NAO conjugates for selective drug delivery in mitochondria-targeted cancer therapy

    Nanoscale, Vol. 14, Núm. 22, pp. 8028-8040

2021

  1. Conservation of Aging and Cancer Epigenetic Signatures across Human and Mouse

    Molecular Biology and Evolution, Vol. 38, Núm. 8, pp. 3415-3435

  2. Integrative methylome-transcriptome analysis unravels cancer cell vulnerabilities in infant MLLrearranged B cell acute lymphoblastic leukemia

    Journal of Clinical Investigation, Vol. 131, Núm. 13

2020

  1. The mTOR pathway is necessary for survival of mice with short telomeres

    Nature Communications, Vol. 11, Núm. 1

2019

  1. Chromatin regulation by Histone H4 acetylation at Lysine 16 during cell death and differentiation in the myeloid compartment

    Nucleic Acids Research, Vol. 47, Núm. 10, pp. 5016-5037

  2. Safety of Whole-Body Abrogation of the TRF1 Shelterin Protein in Wild-Type and Cancer-Prone Mouse Models

    iScience, Vol. 19, pp. 572-585

2018

  1. Enhanced cytotoxic activity of mitochondrial mechanical effectors in human lung carcinoma H520 cells: Pharmaceutical implications for cancer therapy

    Frontiers in Oncology, Vol. 8, Núm. NOV

  2. Therapeutic effects of telomerase in mice with pulmonary fibrosis induced by damage to the lungs and short telomeres

    eLife, Vol. 7

2016

  1. A genetic interaction between RAP1 and telomerase reveals an unanticipated role for RAP1 in telomere maintenance

    Aging Cell, Vol. 15, Núm. 6, pp. 1113-1125

  2. G6PD protects from oxidative damage and improves healthspan in mice

    Nature Communications, Vol. 7

2015

  1. Loss of Tribbles pseudokinase-3 promotes Akt-driven tumorigenesis via FOXO inactivation

    Cell Death and Differentiation, Vol. 22, Núm. 1, pp. 131-144

  2. Mice with Pulmonary Fibrosis Driven by Telomere Dysfunction

    Cell Reports, Vol. 12, Núm. 2, pp. 286-299

  3. Role of cannabinoid receptor CB<inf>2</inf> in HER2 pro-oncogenic signaling in breast cancer

    Journal of the National Cancer Institute, Vol. 107, Núm. 6

  4. TRIB3 suppresses tumorigenesis by controlling mTORC2/AKT/FOXO signaling

    Molecular and Cellular Oncology, Vol. 2, Núm. 3

  5. Therapeutic inhibition of TRF1 impairs the growth of p53-deficient K-RasG12V-induced lung cancer by induction of telomeric DNA damage

    EMBO Molecular Medicine, Vol. 7, Núm. 7, pp. 930-949