Efectividad del lavado de manos prequirurgico en la reduccion de la carga bacteriana, utilizando digluconato de clorrexidina y parachlorometaxylenol
- Martín Aragón, Laura
- Davinia Vicente Campos Director
- Ricardo Becerro de Bengoa Vallejo Director
Defence university: Universidad Complutense de Madrid
Fecha de defensa: 08 November 2016
- Ana Vos Arenillas Chair
- Ramón del Gallego Lastra Secretary
- David Rodríguez Sanz Committee member
- Rubén Sánchez Gómez Committee member
- Inmaculada Corral Liria Committee member
Type: Thesis
Abstract
Introduction: Semmelweis established basis of hospital-acquired diseases. In 19th century, Lister demostrated the effect of hand antisepsis on reduction of SSI. Despite a paucity of appropriate randomized, controlled trials, there is substantial evidence that hand antisepsis reduces the incidence of health care-associated infection. Nowadays, there are 5 commercialized products for preoperative asepsis which contain alcohol, chlorhexidine, iodine/iodophors, parachlorometaxylenol and triclosan. However, no one is ideal for all situation. The aim of this study is to determine whether the antiseptic 3% PCMX has the same bactericidal efficacy than the antiseptic 4% CHG after surgical scrub. Methods: experimental study with quasi-experimental design, and pre-intervention and post-intervention assessment. The sample consisted in 20 healthy adult volunteers. Independent variables: antiseptic solutions used. Dependent variables: bacterial counts sampled immediately after surgical hand disinfecion, 3 hours after, and the difference between bacterial load befores, immediately after and 3 hours after surgical hand disinfection. The study was conducted following the UNE-EN 12791. Results: homogeneus samples was assummed. There were no statistcally significant differences in bacterial load between 3% PCMX and 4% CHG on its immediate effect or 3 hours after. There were statistically significant differences between 60% propanol-1, and 3% PCMX and, 4% CHG, both its immediate effect and 3 hours after. 60% propanol-1 was more effective. Conclusions: 3% PCMX has a bactericidal efficacy similar to 4% CHG both its immediate as 3 hours effect, with a gloved hand, not getting statistically significant differences between these two antiseptics. Propanol-1 60% have greater bactericidal efficacy.