Genetic association study within the framework of Zuckerman's psychobiological personality model

  1. Luis F. García 1
  2. Anton Aluja 2
  3. Oscar García 2
  4. Lara Cuevas 3
  1. 1 Universidad Autónoma de Madrid, España
  2. 2 Institut of Biomedical Research of Lleida, España
  3. 3 Complutense University of Madrid, España
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Revista:
Anuario de psicología

ISSN: 0066-5126

Año de publicación: 2016

Volumen: 46

Número: 1

Páginas: 17-30

Tipo: Artículo

DOI: 10.1016/J.ANPSIC.2016.06.003 DIALNET GOOGLE SCHOLAR lock_openAcceso abierto editor

Otras publicaciones en: Anuario de psicología

Resumen

Partiendo del modelo de personalidad psicobiológico de Zuckerman se planean una serie de hipótesis de la asociación genética de diferentes polimorfismos de la serotonina, testosterona, dopamina, MAO-A y COMT, y tres rasgos temperamentales (Búsqueda impulsiva de sensaciones no socializada, Neuroticismo y Extroversión-sociabilidad). Para superar limitaciones anteriores de este tipo de estudios: 1) la medida fenotípica se mejoró usando ocho escalas para medir los constructos de personalidad, y 2) algunos análisis estadísticos fueron usados para estudiar conjuntamente los efectos de los polimorfismos. La muestra analizada se compuso de 252 participantes de dos muestras de hombres, una de 147 presos y otra de 105 voluntarios sanos. Los resultados informan que cuando se consideran conjuntamente todos los polimorfismos estu-diados se observa una tendencia en la dirección de las hipótesis formuladas. La sección de la discusión recomienda aplicar variables más integradoras para explorar los caminos complejos de las genéticas a la conducta.

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Fuente de los datos: Dialnet