Effect of sex and age on fatty acid composition of Iberian swine foetuses exposed to maternal malnutrition

  1. García-Contreras, C. 1
  2. Vázquez-Gómez, M. 2
  3. Astiz, S. 1
  4. Torres-Rovira, L. 1
  5. Isabel, B. 2
  6. Óvilo, C. 1
  7. González-Bulnes, A. 1
  1. 1 INIA. Madrid. Spain.
  2. 2 UCM. Faculty of Veterinary. Madrid. Spain.
Revista:
Archivos de zootecnia

ISSN: 0004-0592,  1885-4494

Año de publicación: 2018

Número: 1

Páginas: 109-113

Tipo: Artículo

DOI: 10.21071/AZ.V67ISUPPLEMENT.3584 DIALNET GOOGLE SCHOLAR lock_openDialnet editor

Otras publicaciones en: Archivos de zootecnia

Objetivos de desarrollo sostenible

Resumen

Intrauterine growth restriction (IUGR) is the consequence of inadequate placental supply of oxygen and/or nutrients during prenatal development. The adaptive response of the offspring is time-dependent, but there is also increasing evidence of a strong modulation by sex. The present study aimed to determine time-related changes and sex-related differences in fatty acid composition at non-adipose tissues involved in metabolism regulation during the development of IUGR fetuses. For that, we analyzed the liver and muscle (longissimus dorsi) fatty acids composition of IUGRs foetuses (obtained as consequence of maternal malnutrition) throughout pregnancy (Day 70 vs. 90) and sex-related effects (male vs. female). The final distribution of sampled foetuses was: 33 foetuses at Day 70 of pregnancy (13 females and 20 males), and 23 foetuses at Day 90, (10 females and 13 males). Both in liver and muscle a higher concentration of saturated fatty acids (SFA; P

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Información de financiación

The experimental work was supported by funds from the Ministry of Economy and Competitiveness (project AGL2013-48121-C3-0-R), co-funded by FEDER. The funders had no role in study design, data collection and analysis, decision to publish, or preparation of the manuscript. The authors thank the INIA animal staff for his assistance with animal care and P. Cuesta and I. Cano (Department of Research Support, Univer-sidad Complutense de Madrid) for statistical analyses.

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