Therapeutic impact of colon capsule endoscopy with PillCam™ COLON 2 after incomplete standard colonoscopya Spanish multicenter study

  1. Óscar Nogales Rincón 1
  2. J. García Lledó 1
  3. Marisol Luján-Sanchis 2
  4. D. Nicolás Pérez 3
  5. José Francisco Juanmartiñena Fernández 4
  6. Begoña González Suárez 5
  7. Francisco L. Sánchez Ceballos 6
  8. Ignacio Couto Wörner 7
  9. José Olmedo Camacho 8
  10. María Cristina Garfía Castillo 9
  11. Cristina Carretero Ribón 10
  12. Ignacio Fernández Urién 4
  13. Sarbelio Rodríguez Muloz 9
  14. Matilde Asteinza Daganzo 6
  15. Mª del Pilar Olivencia Palomar 11
  16. Ángeles Masedo González 9
  17. Miguel Ángel Muñoz Navas 12
  18. Beatriz Merino Rodríguez 1
  19. Cecilia González Asanza 1
  1. 1 Hospital General Universitario Gregorio Marañón. Madrid, Spain
  2. 2 Hospital General Universitario de Valencia
    info

    Hospital General Universitario de Valencia

    Valencia, España

    ROR https://ror.org/03sz8rb35

  3. 3 Hospital Universitario de Canarias
    info

    Hospital Universitario de Canarias

    San Cristóbal de La Laguna, España

    ROR https://ror.org/05qndj312

  4. 4 Hospital de Navarra. Pamplona, Spain
  5. 5 Hospital Clinic Barcelona
    info

    Hospital Clinic Barcelona

    Barcelona, España

    ROR https://ror.org/02a2kzf50

  6. 6 Hospital Clínico San Carlos. Madrid, Spain
  7. 7 Complexo Hospitalario Universitario A Coruña. Spain
  8. 8 Hospital General Universitario de Ciudad Real. Ciudad Real, Spain
  9. 9 Hospital Universitario 12 de Octubre. Madrid
  10. 10 Clínica Universidad de Navarra. Pamplona, Spain
  11. 11 Hospital General de Ciudad Real
    info

    Hospital General de Ciudad Real

    Ciudad Real, España

    ROR https://ror.org/02f30ff69

  12. 12 Universidad de Navarra. Pamplona
Revista:
Revista Española de Enfermedades Digestivas

ISSN: 2340-416 1130-0108

Año de publicación: 2017

Volumen: 109

Número: 5

Páginas: 322-327

Tipo: Artículo

DOI: 10.17235/REED.2017.4369/2016 DIALNET GOOGLE SCHOLAR

Otras publicaciones en: Revista Española de Enfermedades Digestivas

Resumen

Introduction: Colon capsule endoscopy (CCE) is an alternative approach for the examination of the colon in patients who refuse colonoscopy or after incomplete colonoscopy (IC). We conducted a study to determine the frequency of complete colonoscopy after IC, the diagnostic yield of CCE, the therapeutic impact of lesions found in CCE, the level of colon cleanliness and the safety of the procedure. Methods: We performed a prospective, multicenter study involving ten Spanish hospitals. Consecutive outpatients aged ≥ 18 years with previous IC were invited to participate. The latest version of the CCE device, PillCam™ COLON 2 (CCE-2), was administered to all patients according to the protocol. Results: The study population comprised 96 patients. The most frequent cause of IC was the inability to move past a loop using standard maneuvers (75/96 patients, 78%). Complete visualization of the colon was obtained with CCE-2 in 69 patients (71.9%). Of the 27 patients in whom the CCE-2 did not reach the hemorrhoidal plexus, it passed the colonic segment explored with the previous colonoscopy in 20 cases; therefore, it could be inferred that a combined approach (CCE-2 plus colonoscopy) enabled complete visualization of the colonic mucosa in 92.7% of patients. CCE-2 revealed new lesions in 58 patients (60.4%). Polyps were the most frequent finding (41 patients; 42.7% of the total number of patients). In 43 of the 58 patients (44.8% of the total number of patients), the new lesions observed led to modification of therapy, which included a new colonoscopy for polyp resection or surgery in patients with colonic neoplasm. Conclusions: CCE-2 is a suitable diagnostic procedure that can lead to more frequent diagnosis of significant colonic lesions after IC.