La enfermedad del ojo seco en pacientes con y sin fibromialgiaestudio comparativo

  1. Muñoz Hernandez, Ana Maria
Supervised by:
  1. José Manuel Benítez del Castillo Sánchez Director
  2. Francisco Sáenz-Francés San Baldomero Director
  3. Enrique Santos Bueso Director

Defence university: Universidad Complutense de Madrid

Fecha de defensa: 27 November 2020

Committee:
  1. Julián García Sánchez Chair
  2. Vanessa Andrés Guerrero Secretary
  3. E. Vico-Ruíz Committee member
  4. Elena García-Martin Committee member
  5. María del Rocío García Catalán Committee member
Department:
  1. Inmunología, Oftalmología y ORL

Type: Thesis

Abstract

Dry eye disease (DED) is one of the most common and relevant ophthalmological conditions in the population, due both to its clinical and economic consequences. It is estimated that 5 to 50 percent of the population is affected (75% if we consider asymptomatic patients who present signs), being more frequent in Hispanics and Asians. It mainly affects women and is aggravated by age. In the latest Tear Film & Ocular Surface Society (TFOS) report, the 2017 Dry Eye Workshop (DEWS II), it is defined as “a multifactorial disease of the ocular surface characterized by a loss of homeostasis of the tear film, and accompanied by ocular symptoms, in which tear filmin stability and hyperosmolarity, ocular surface inflammation and damage, and neurosensory abnormalities play etiological roles”. Although traditionally it has been classified as evaporative dry eye (the most frequent cause is the Meibomian glands dysfunction [MGD]) and aqueous‐deficient dry eye, the latest DEWS has established a mixed classification, with the predominance of one type or another. The suffering of this chronic disease implies a significant impairment of the quality of life, due to both visual disturbances as well as the physical and psychological consequences of the pain. Therefore, people’s work productivity decreases...