Infiltración meníngea de linfoma linfoplasmocíticosíndrome de Bing-Neel

  1. Raquel Behar Lagares
  2. Carlos Lombardía González
  3. María Cruz Cárdenas Fernández
  4. Celina Benavente
Revista:
Revista del laboratorio clínico

ISSN: 1888-4008

Any de publicació: 2017

Volum: 10

Número: 1

Pàgines: 49-54

Tipus: Article

DOI: 10.1016/J.LABCLI.2016.09.005 DIALNET GOOGLE SCHOLAR

Altres publicacions en: Revista del laboratorio clínico

Resum

Waldenström macroglobulinemia is a lymphoplasmacytic lymphoma defined by a monoclonal proliferation of bone marrow infiltrating immunoglobulin M producing B lymphocytes. Neurological simptoms of Waldenström macroglobulinemia are mainly dominated by signs of hyperviscosity and autoimmune neuropathies mediated by immunoglobulin M. Neurological involvement secondary to the infiltration of IgM producing B lymphocytes, is defined as a Bing-Neel syndrome. This syndrome has a low prevalence and the clinical manifestations are variable. The case described is about a 76 year-old female with a history of Waldenström macroglobulinemia, who presents sudden neurological signs such as alteration of spoken language and clumsiness of the right hand. The clinical laboratory has a primary role in the diagnosis of Bing-Neel syndrome and monitoring of the treatment.

Fuente de los datos: Dialnet