Criterios de fragilidad en mayores tras una intervención dirigida al control ponderal y cambios en el estilo de vida

  1. CUESTA TRIANA, FEDERICO MIGUEL
Supervised by:
  1. Miguel Angel Rubio Herrera Director
  2. Pilar Matía Martín Director
  3. José Manuel Ribera Casado Director

Defence university: Universidad Complutense de Madrid

Fecha de defensa: 30 May 2022

Committee:
  1. Pedro Gil Gregorio Chair
  2. Carlos Verdejo Bravo Secretary
  3. Alfonso José Cruz Jentoft Committee member
  4. Jordi Salas Salvadó Committee member
  5. Julia Álvarez Hernández Committee member

Type: Thesis

Abstract

In recent years the interest in syndromes such as frailty has become evident. The most interesting aspect is to recognize this entity in the approach to chronic disease, where small interventions achieve real improvements in different domains. This fact is especially interesting in topics like comorbidity, which favors the vulnerability of the individual, not only from a medical point of view but also considering the psychological, functional, and even psychosocial domains. Different authors have published about fragility, understanding it as a clinical state in which a special vulnerability to exogenous and endogenous stressors is detected. It is noteworthy that the same stimulus can provoke different consequences in the individuals depending on their susceptibility.There are many approaches about this topic. The most classic has been based on a description of phenotypes, although from a practical point of view the application of any measure must consider the context of its application, clinical practice, or research. One of the most attractive aspects is to consider frailty as a dynamic conception. This approach allows to establish preventive and therapeutic measures to delay or even reverse these situations. In this work, the intervention is based on the application of a healthy diet model, called Mediterranean diet, on a group of individuals who also have metabolic syndrome, with the aim of assessing its effect on progression and regression of frailty or its previous phase called prefrailty...