Determinación de IgE, IgG4, IgG e IgA específica en pacientes con anisakiosis gastroalérgica y urticaria crónica asociada a sensibilización al parásito Anisakis simplex

  1. ULLATE SANZ, LAURA
Supervised by:
  1. Marta Rodero Martínez Director
  2. Carmen Cuéllar del Hoyo Director

Defence university: Universidad Complutense de Madrid

Fecha de defensa: 29 June 2022

Committee:
  1. Francisco Bolas Fernández Chair
  2. Juan José García Rodríguez Secretary
  3. Javier Sotillo Gallego Committee member
  4. Fernanda Romaris Martínez Committee member
  5. Soledad Fenoy Rodríguez Committee member

Type: Thesis

Teseo: 745964 DIALNET lock_openDocta Complutense editor

Abstract

Anisakiosis is defined as the human disease caused by the accidental ingestion of live third-stage larvae of anisakids (Anisakis) due to the consumption of raw or undercooked fish. It can trigger both different phenotypes acute urticaria and chronic urticaria, depending on the host's immune response.Gastro-allergic Anisakiosis (GAA) is characterized by an acute allergic reaction (urticaria, angioedema, anaphylaxis), generally lasting less than 48 hours, which may be accompanied by digestive symptoms. Chronic Urticaria associated with sensitization to Anisakis simplex (CU+) shows prolonged and chronic urticarial manifestations. Both pathologies are caused by contact with the live larvae of the parasite, and currently have an estimated prevalence of 0.6% and an accumulated incidence of 2.9% in Spain...