Evaluación de la Inmunodeficiencia Secundaria en Trasplante de Órgano Sólido.Detección y Reconstitución

  1. JIMÉNEZ LÓPEZ, MARICELA
Supervised by:
  1. Javier Alberto Carbone Campoverde Director

Defence university: Universidad Complutense de Madrid

Fecha de defensa: 27 April 2022

Committee:
  1. Edgar Fernández Malavé Chair
  2. Manuel Ruiz Fernandez Secretary
  3. Amelia Hessheimer Committee member
  4. César Rodríguez Hernandez Committee member
  5. Manuel Hernández González Committee member

Type: Thesis

Teseo: 780156 DIALNET

Abstract

Solid organ transplantation is currently a well-established therapy for patients with terminal diseases. The combination of immunosuppression, surgical risks, circulatory assistances, and transplant complications predispose this population to infectious complications and sequelae of clinical importance, because of this, early and specific diagnosis is essential for adequate clinical results and could benefit from personalized medicine with immunologic monitoring. Hypothesis and objectives: Measurement of immunological, hematological, and biochemical biomarkers are useful to identify patients who are at risk of infections in the post-transplant period. The main objective of this study is to evaluate the use of immunological and biochemical biomarkers of secondary immunodeficiency that influence the prediction of infections in patients with solid organ transplants in different hospital centers...