Evaluación de la Inmunodeficiencia Secundaria en Trasplante de Órgano Sólido.Detección y Reconstitución
- JIMÉNEZ LÓPEZ, MARICELA
- Javier Alberto Carbone Campoverde Director
Universidade de defensa: Universidad Complutense de Madrid
Fecha de defensa: 27 de abril de 2022
- Edgar Fernández Malavé Presidente
- Manuel Ruiz Fernandez Secretario
- Amelia Hessheimer Vogal
- César Rodríguez Hernandez Vogal
- Manuel Hernández González Vogal
Tipo: Tese
Resumo
Solid organ transplantation is currently a well-established therapy for patients with terminal diseases. The combination of immunosuppression, surgical risks, circulatory assistances, and transplant complications predispose this population to infectious complications and sequelae of clinical importance, because of this, early and specific diagnosis is essential for adequate clinical results and could benefit from personalized medicine with immunologic monitoring. Hypothesis and objectives: Measurement of immunological, hematological, and biochemical biomarkers are useful to identify patients who are at risk of infections in the post-transplant period. The main objective of this study is to evaluate the use of immunological and biochemical biomarkers of secondary immunodeficiency that influence the prediction of infections in patients with solid organ transplants in different hospital centers...