Publicacions en col·laboració amb investigadors/es de University of St Andrews (11)

2020

  1. Synthesis, biological evaluation, and molecular modeling of nitrile-containing compounds: Exploring multiple activities as anti-Alzheimer agents

    Drug Development Research, Vol. 81, Núm. 2, pp. 215-231

2018

  1. Evidence for a cyanine link between propargylamine drugs and monoamine oxidase clarifies the inactivation mechanism

    Frontiers in Chemistry, Vol. 6, Núm. MAY

2017

  1. Comparative Analysis of the Neurochemical Profile and MAO Inhibition Properties of N-(Furan-2-ylmethyl)-N-methylprop-2-yn-1-amine

    ACS Chemical Neuroscience, Vol. 8, Núm. 5, pp. 1026-1035

  2. Multitarget-Directed Ligands Combining Cholinesterase and Monoamine Oxidase Inhibition with Histamine H3R Antagonism for Neurodegenerative Diseases

    Angewandte Chemie - International Edition, Vol. 56, Núm. 41, pp. 12765-12769

2016

  1. ASS234, as a new multi-target directed propargylamine for Alzheimer's disease therapy

    Frontiers in Neuroscience, Vol. 10, Núm. JUN

  2. Design, Synthesis and in vitro Evaluation of Indolotacrine Analogues as Multitarget-Directed Ligands for the Treatment of Alzheimer's Disease

    ChemMedChem, pp. 1264-1269

  3. Multi-target directed donepezil-like ligands for Alzheimer's disease

    Frontiers in Neuroscience, Vol. 10, Núm. MAY

2015

  1. Predicting targets of compounds against neurological diseases using cheminformatic methodology

    Journal of Computer-Aided Molecular Design, Vol. 29, Núm. 2, pp. 183-198

2014

  1. Exploring the structural basis of the selective inhibition of monoamine oxidase A by dicarbonitrile aminoheterocycles: Role of Asn181 and Ile335 validated by spectroscopic and computational studies

    Biochimica et Biophysica Acta - Proteins and Proteomics, Vol. 1844, Núm. 2, pp. 389-397

  2. Kinetic and structural analysis of the irreversible inhibition of human monoamine oxidases by ASS234, a multi-target compound designed for use in Alzheimer's disease

    Biochimica et Biophysica Acta - Proteins and Proteomics, Vol. 1844, Núm. 6, pp. 1104-1110

  3. N-methyl-N-((1-methyl-5-(3-(1-(2-methylbenzyl)piperidin-4-yl)propoxy)-1H-indol-2-yl)methyl)prop-2-yn-1-amine, a new cholinesterase and monoamine oxidase dual inhibitor

    Journal of Medicinal Chemistry, Vol. 57, Núm. 24, pp. 10455-10463