Instituto de Química Médica -ko ikertzaileekin lankidetzan egindako argitalpenak (17)

2019

  1. Acid-base behaviour and binding to double stranded DNA/RNA of benzo[g]phthalazine-based ligands

    New Journal of Chemistry, Vol. 43, Núm. 2, pp. 700-708

2015

  1. Imidazole-containing phthalazine derivatives inhibit Fe-SOD performance in Leishmania species and are active in vitro against visceral and mucosal leishmaniasis

    Parasitology, Vol. 142, Núm. 8, pp. 1115-1129

  2. Synthesis and evaluation of in vitro and in vivo trypanocidal properties of a new imidazole-containing nitrophthalazine derivative

    European Journal of Medicinal Chemistry, Vol. 106, pp. 106-119

2014

  1. In vitro leishmanicidal activity of pyrazole-containing polyamine macrocycles which inhibit the Fe-SOD enzyme of Leishmania infantum and Leishmania braziliensis species

    Parasitology, Vol. 141, Núm. 8, pp. 1031-1043

2012

  1. In vitro leishmanicidal activity of imidazole- or pyrazole-based benzo[g]phthalazine derivatives against leishmania infantum and leishmania braziliensis species

    Journal of Antimicrobial Chemotherapy, Vol. 67, Núm. 2, pp. 387-397

  2. Phthalazine derivatives containing imidazole rings behave as Fe-SOD inhibitors and show remarkable anti-T. cruzi activity in immunodeficient-mouse mode of infection

    Journal of Medicinal Chemistry, Vol. 55, Núm. 22, pp. 9900-9913

2011

  1. Hydrogen-bond-mediated self-assembly of 26-membered diaza tetraester crowns of 3,5-disubstituted 1 h -pyrazole. Dimerization study in the solid state and in CDCl 3 solution

    Journal of Organic Chemistry, Vol. 76, Núm. 20, pp. 8223-8231

  2. In vivo trypanosomicidal activity of imidazole- or pyrazole-based benzo[ g ]phthalazine derivatives against acute and chronic phases of chagas disease

    Journal of Medicinal Chemistry, Vol. 54, Núm. 4, pp. 970-979

2010

  1. Synthesis and cytotoxic activity of a new potential DNA bisintercalator: 1,4-Bis{3-[N-(4-chlorobenzo[g]phthalazin-1-yl)aminopropyl]}piperazine

    Bioorganic and Medicinal Chemistry, Vol. 18, Núm. 14, pp. 5301-5309

2008

  1. Diazatetraester 1H-pyrazole crowns as fluorescent chemosensors for AMPH, METH, MDMA (Ecstasy), and dopamine

    Organic Letters, Vol. 10, Núm. 22, pp. 5099-5102

  2. Efficient inhibition of iron superoxide dismutase and of Trypanosoma cruzi growth by benzo[g]phthalazine derivatives functionalized with one or two imidazole rings

    Journal of Medicinal Chemistry, Vol. 51, Núm. 6, pp. 1962-1966

2007

  1. 1,4-Bis(alkylamino)benzo[g]phthalazines able to form dinuclear complexes of Cu(II) which as free ligands behave as SOD inhibitors and show efficient in vitro activity against Trypanosoma cruzi

    Bioorganic and Medicinal Chemistry, Vol. 15, Núm. 5, pp. 2081-2091

2005

  1. CuII and ZnII coordination chemistry of pyrazole-containing polyamine receptors - Influence of the hydrocarbon side chain length on the metal coordination

    European Journal of Inorganic Chemistry, pp. 189-208

  2. New acyclic receptors containing pyridazine units. The influence of π-stacking on the selective transport of lipophilic phenethylamines

    Tetrahedron, Vol. 61, Núm. 50, pp. 11965-11975

2004

  1. A new series of heteroaromatic receptors containing the 1,3-bis(6-oxopyridazin-1-yl)propane unit: Their selective transport ability towards NH4+ in relation to Na+, K+ and Ca2+

    Tetrahedron, Vol. 60, Núm. 4, pp. 979-986

  2. New 1H-Pyrazole-Containing Polyamine Receptors Able to Complex L-Glutamate in Water at Physiological pH Values

    Journal of the American Chemical Society, Vol. 126, Núm. 3, pp. 823-833

2003

  1. Synthesis and cytotoxic activity of N,N-bis-{3-[N-(4-chlorobenzo[g]-phthalazin-1-yl)]aminopropyl}-N-methylamine: A new potential DNA bisintercalator

    Bioorganic and Medicinal Chemistry, Vol. 11, Núm. 10, pp. 2143-2148