MARÍA JOSEFA
RODRÍGUEZ YUNTA
Profesora titular de universidad
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Instituto de Química Médica
Madrid, EspañaPublicacións en colaboración con investigadores/as de Instituto de Química Médica (17)
2019
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Acid-base behaviour and binding to double stranded DNA/RNA of benzo[g]phthalazine-based ligands
New Journal of Chemistry, Vol. 43, Núm. 2, pp. 700-708
2015
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Imidazole-containing phthalazine derivatives inhibit Fe-SOD performance in Leishmania species and are active in vitro against visceral and mucosal leishmaniasis
Parasitology, Vol. 142, Núm. 8, pp. 1115-1129
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Synthesis and evaluation of in vitro and in vivo trypanocidal properties of a new imidazole-containing nitrophthalazine derivative
European Journal of Medicinal Chemistry, Vol. 106, pp. 106-119
2014
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In vitro leishmanicidal activity of pyrazole-containing polyamine macrocycles which inhibit the Fe-SOD enzyme of Leishmania infantum and Leishmania braziliensis species
Parasitology, Vol. 141, Núm. 8, pp. 1031-1043
2012
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In vitro leishmanicidal activity of imidazole- or pyrazole-based benzo[g]phthalazine derivatives against leishmania infantum and leishmania braziliensis species
Journal of Antimicrobial Chemotherapy, Vol. 67, Núm. 2, pp. 387-397
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Phthalazine derivatives containing imidazole rings behave as Fe-SOD inhibitors and show remarkable anti-T. cruzi activity in immunodeficient-mouse mode of infection
Journal of Medicinal Chemistry, Vol. 55, Núm. 22, pp. 9900-9913
2011
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Hydrogen-bond-mediated self-assembly of 26-membered diaza tetraester crowns of 3,5-disubstituted 1 h -pyrazole. Dimerization study in the solid state and in CDCl 3 solution
Journal of Organic Chemistry, Vol. 76, Núm. 20, pp. 8223-8231
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In vivo trypanosomicidal activity of imidazole- or pyrazole-based benzo[ g ]phthalazine derivatives against acute and chronic phases of chagas disease
Journal of Medicinal Chemistry, Vol. 54, Núm. 4, pp. 970-979
2010
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Synthesis and cytotoxic activity of a new potential DNA bisintercalator: 1,4-Bis{3-[N-(4-chlorobenzo[g]phthalazin-1-yl)aminopropyl]}piperazine
Bioorganic and Medicinal Chemistry, Vol. 18, Núm. 14, pp. 5301-5309
2008
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Diazatetraester 1H-pyrazole crowns as fluorescent chemosensors for AMPH, METH, MDMA (Ecstasy), and dopamine
Organic Letters, Vol. 10, Núm. 22, pp. 5099-5102
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Efficient inhibition of iron superoxide dismutase and of Trypanosoma cruzi growth by benzo[g]phthalazine derivatives functionalized with one or two imidazole rings
Journal of Medicinal Chemistry, Vol. 51, Núm. 6, pp. 1962-1966
2007
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1,4-Bis(alkylamino)benzo[g]phthalazines able to form dinuclear complexes of Cu(II) which as free ligands behave as SOD inhibitors and show efficient in vitro activity against Trypanosoma cruzi
Bioorganic and Medicinal Chemistry, Vol. 15, Núm. 5, pp. 2081-2091
2005
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CuII and ZnII coordination chemistry of pyrazole-containing polyamine receptors - Influence of the hydrocarbon side chain length on the metal coordination
European Journal of Inorganic Chemistry, pp. 189-208
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New acyclic receptors containing pyridazine units. The influence of π-stacking on the selective transport of lipophilic phenethylamines
Tetrahedron, Vol. 61, Núm. 50, pp. 11965-11975
2004
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A new series of heteroaromatic receptors containing the 1,3-bis(6-oxopyridazin-1-yl)propane unit: Their selective transport ability towards NH4+ in relation to Na+, K+ and Ca2+
Tetrahedron, Vol. 60, Núm. 4, pp. 979-986
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New 1H-Pyrazole-Containing Polyamine Receptors Able to Complex L-Glutamate in Water at Physiological pH Values
Journal of the American Chemical Society, Vol. 126, Núm. 3, pp. 823-833
2003
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Synthesis and cytotoxic activity of N,N-bis-{3-[N-(4-chlorobenzo[g]-phthalazin-1-yl)]aminopropyl}-N-methylamine: A new potential DNA bisintercalator
Bioorganic and Medicinal Chemistry, Vol. 11, Núm. 10, pp. 2143-2148