Publications (90) MARÍA JESÚS OSET GASQUE publications

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2025

  1. Cholinesterase-based inhibitors as multitarget small molecules for the therapy of Alzheimer's disease

    Chemico-Biological Interactions, Vol. 413

2024

  1. A methodology to globally assess ectodomain shedding using soluble fractions from the mouse brain

    Frontiers in Psychiatry, Vol. 15

  2. Design and Synthesis of Multi-Functional Ligands through Hantzsch Reaction: Targeting Ca2+ Channels, Activating Nrf2 and Possessing Cathepsin S Inhibitory, and Antioxidant Properties

    Pharmaceutics, Vol. 16, Núm. 1

  3. In Vitro Modulation of Autophagy by New Antioxidant Nitrones as a Potential Therapeutic Approach for the Treatment of Ischemic Stroke

    Antioxidants, Vol. 13, Núm. 8

2023

  1. Neuroprotective and Antioxidant Properties of CholesteroNitrone ChN2 and QuinolylNitrone QN23 in an Experimental Model of Cerebral Ischemia: Involvement of Necrotic and Apoptotic Cell Death

    Antioxidants, Vol. 12, Núm. 7

  2. Neuroprotective and antioxidant properties of new quinolylnitrones in in vitro and in vivo cerebral ischemia models

    Scientific Reports, Vol. 13, Núm. 1

  3. The activation of mGluR4 rescues parallel fiber synaptic transmission and LTP, motor learning and social behavior in a mouse model of Fragile X Syndrome

    Molecular autism, Vol. 14, Núm. 1, pp. 14

2022

  1. Nucleobase-Derived Nitrones: Synthesis and Antioxidant and Neuroprotective Activities in an In Vitro Model of Ischemia–Reperfusion

    International Journal of Molecular Sciences, Vol. 23, Núm. 6

2021

  1. Synthesis, Neuroprotection, and Antioxidant Activity of 1,1'-Biphenylnitrones as α-Phenyl-N-tert-butylnitrone Analogues in In Vitro Ischemia Models

    Molecules (Basel, Switzerland), Vol. 26, Núm. 4

  2. Use of Radical Oxygen Species Scavenger Nitrones to Treat Oxidative Stress-Mediated Hearing Loss: State of the Art and Challenges

    Frontiers in Cellular Neuroscience, Vol. 15

2020

  1. Homo-tris-nitrones derived from α-phenyl-n-tert-butylnitrone: Synthesis, neuroprotection and antioxidant properties

    International Journal of Molecular Sciences, Vol. 21, Núm. 21, pp. 1-18

  2. Neuroprotection by phytoestrogens in the model of deprivation and resupply of oxygen and glucose in vitro: The contribution of autophagy and related signaling mechanisms

    Antioxidants, Vol. 9, Núm. 6, pp. 1-20

  3. Synthesis, antioxidant properties and neuroprotection of α-phenyl-tert-butylnitrone derived HomoBisNitrones in in vitro and in vivo ischemia models

    Scientific Reports, Vol. 10, Núm. 1

  4. Tacrine-natural-product hybrids for alzheimer’s disease therapy

    Current Medicinal Chemistry, Vol. 27, Núm. 26, pp. 4392-4400

2019

  1. Donepezil + chromone + melatonin hybrids as promising agents for Alzheimer’s disease therapy

    Journal of Enzyme Inhibition and Medicinal Chemistry, Vol. 34, Núm. 1, pp. 479-489

  2. Synthesis and Neuroprotective Properties of N-Substituted C-Dialkoxyphosphorylated Nitrones

    ACS Omega, Vol. 4, Núm. 5, pp. 8581-8587

  3. Synthesis of new ferulic/lipoic/comenic acid-melatonin hybrids as antioxidants and Nrf2 activators via Ugi reaction

    Future Medicinal Chemistry, Vol. 11, Núm. 24, pp. 3097-3108

  4. Synthesis, antioxidant and Aβ anti-aggregation properties of new ferulic, caffeic and lipoic acid derivatives obtained by the Ugi four-component reaction

    Bioorganic Chemistry, Vol. 85, pp. 221-228

  5. Synthesis, neuroprotective and antioxidant capacity of PBN-related indanonitrones

    Bioorganic Chemistry, Vol. 86, pp. 445-451

  6. The loss of β adrenergic receptor mediated release potentiation in a mouse model of fragile X syndrome

    Neurobiology of Disease, Vol. 130