MARÍA JESÚS
OSET GASQUE
Catedrática de universidad
Publications (89) MARÍA JESÚS OSET GASQUE publications
2024
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A methodology to globally assess ectodomain shedding using soluble fractions from the mouse brain
Frontiers in Psychiatry, Vol. 15
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Design and Synthesis of Multi-Functional Ligands through Hantzsch Reaction: Targeting Ca2+ Channels, Activating Nrf2 and Possessing Cathepsin S Inhibitory, and Antioxidant Properties
Pharmaceutics, Vol. 16, Núm. 1
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In Vitro Modulation of Autophagy by New Antioxidant Nitrones as a Potential Therapeutic Approach for the Treatment of Ischemic Stroke
Antioxidants, Vol. 13, Núm. 8
2023
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Neuroprotective and Antioxidant Properties of CholesteroNitrone ChN2 and QuinolylNitrone QN23 in an Experimental Model of Cerebral Ischemia: Involvement of Necrotic and Apoptotic Cell Death
Antioxidants, Vol. 12, Núm. 7
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Neuroprotective and antioxidant properties of new quinolylnitrones in in vitro and in vivo cerebral ischemia models
Scientific Reports, Vol. 13, Núm. 1
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The activation of mGluR4 rescues parallel fiber synaptic transmission and LTP, motor learning and social behavior in a mouse model of Fragile X Syndrome
Molecular autism, Vol. 14, Núm. 1, pp. 14
2022
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Nucleobase-Derived Nitrones: Synthesis and Antioxidant and Neuroprotective Activities in an In Vitro Model of Ischemia–Reperfusion
International Journal of Molecular Sciences, Vol. 23, Núm. 6
2021
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Synthesis, Neuroprotection, and Antioxidant Activity of 1,1'-Biphenylnitrones as α-Phenyl-N-tert-butylnitrone Analogues in In Vitro Ischemia Models
Molecules (Basel, Switzerland), Vol. 26, Núm. 4
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Use of Radical Oxygen Species Scavenger Nitrones to Treat Oxidative Stress-Mediated Hearing Loss: State of the Art and Challenges
Frontiers in Cellular Neuroscience, Vol. 15
2020
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Homo-tris-nitrones derived from α-phenyl-n-tert-butylnitrone: Synthesis, neuroprotection and antioxidant properties
International Journal of Molecular Sciences, Vol. 21, Núm. 21, pp. 1-18
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Neuroprotection by phytoestrogens in the model of deprivation and resupply of oxygen and glucose in vitro: The contribution of autophagy and related signaling mechanisms
Antioxidants, Vol. 9, Núm. 6, pp. 1-20
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Synthesis, antioxidant properties and neuroprotection of α-phenyl-tert-butylnitrone derived HomoBisNitrones in in vitro and in vivo ischemia models
Scientific Reports, Vol. 10, Núm. 1
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Tacrine-natural-product hybrids for alzheimer’s disease therapy
Current Medicinal Chemistry, Vol. 27, Núm. 26, pp. 4392-4400
2019
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Donepezil + chromone + melatonin hybrids as promising agents for Alzheimer’s disease therapy
Journal of Enzyme Inhibition and Medicinal Chemistry, Vol. 34, Núm. 1, pp. 479-489
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Synthesis and Neuroprotective Properties of N-Substituted C-Dialkoxyphosphorylated Nitrones
ACS Omega, Vol. 4, Núm. 5, pp. 8581-8587
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Synthesis of new ferulic/lipoic/comenic acid-melatonin hybrids as antioxidants and Nrf2 activators via Ugi reaction
Future Medicinal Chemistry, Vol. 11, Núm. 24, pp. 3097-3108
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Synthesis, antioxidant and Aβ anti-aggregation properties of new ferulic, caffeic and lipoic acid derivatives obtained by the Ugi four-component reaction
Bioorganic Chemistry, Vol. 85, pp. 221-228
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Synthesis, neuroprotective and antioxidant capacity of PBN-related indanonitrones
Bioorganic Chemistry, Vol. 86, pp. 445-451
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The loss of β adrenergic receptor mediated release potentiation in a mouse model of fragile X syndrome
Neurobiology of Disease, Vol. 130
2018
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Alzheimer's Disease, the "one-Molecule, One-Target" Paradigm, and the Multitarget Directed Ligand Approach
ACS Chemical Neuroscience, Vol. 9, Núm. 3, pp. 401-403