JOSÉ CARLOS
MENÉNDEZ RAMOS
Catedrático de universidad
MARÍA PILAR
LÓPEZ-ALVARADO GUTIÉRREZ
Catedrática de universidad
Publications dans lesquelles il/elle collabore avec MARÍA PILAR LÓPEZ-ALVARADO GUTIÉRREZ (52)
2024
2023
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A New Method for the Introduction of an Acylsulfonamide Moiety Applied to a 3-Substituted Functionalized Indole Framework Related to the Welwitindolinone Alkaloids
Synlett, Vol. 34, Núm. 16, pp. 1920-1924
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Small-molecule theranostics in Alzheimer's disease
European Journal of Medicinal Chemistry, Vol. 255
2022
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Multitarget Hybrid Fasudil Derivatives as a New Approach to the Potential Treatment of Amyotrophic Lateral Sclerosis
Journal of Medicinal Chemistry, Vol. 65, Núm. 3, pp. 1867-1882
2021
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Emerging targets in drug discovery against neurodegenerative diseases: Control of synapsis disfunction by the RhoA/ROCK pathway
European Journal of Medicinal Chemistry, Vol. 225
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Human amylin aggregates release within exosomes as a protective mechanism in pancreatic β cells: Pancreatic β-hippocampal cell communication
Biochimica et Biophysica Acta - Molecular Cell Research, Vol. 1868, Núm. 5
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One-Pot Mechanochemical Synthesis of Mono- and Bis-Indolylquinones via Solvent-Free Multiple Bond-Forming Processes
ChemSusChem, Vol. 14, Núm. 21, pp. 4764-4775
2019
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Structure-activity relationships and mechanistic studies of novel mitochondria-targeted, leishmanicidal derivatives of the 4-aminostyrylquinoline scaffold
European Journal of Medicinal Chemistry, Vol. 171, pp. 38-53
2018
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4TM-TRPM8 channels are new gatekeepers of the ER-mitochondria Ca2+ transfer
Biochimica et Biophysica Acta - Molecular Cell Research, Vol. 1865, Núm. 7, pp. 981-994
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Tacripyrimidines, the first tacrine-dihydropyrimidine hybrids, as multi-target-directed ligands for Alzheimer's disease
European Journal of Medicinal Chemistry, Vol. 155, pp. 839-846
2017
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A systematic 1H- and 13C-NMR spectral analysis of bicyclo[n.3.1]alkanone systems: Determination of the relative configuration of the stereogenic centres and conformation of the six-membered ring
Magnetic Resonance in Chemistry
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Empleo del Campus Virtual en docencia práctica: una herramienta para una enseñanza universitaria en inglés e inclusiva
Enseñanza de las ciencias: revista de investigación y experiencias didácticas, Núm. 0, pp. 1801-1806
2016
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Tetrahydroisoquinoline-Derived Urea and 2,5-Diketopiperazine Derivatives as Selective Antagonists of the Transient Receptor Potential Melastatin 8 (TRPM8) Channel Receptor and Antiprostate Cancer Agents
Journal of Medicinal Chemistry, Vol. 59, Núm. 12, pp. 5661-5683
2014
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One-pot α-amidosulfone-mediated variation of the pictet-Spengler tetrahydroisoquinoline synthesis, suitable for amide-type substrates
European Journal of Organic Chemistry, Vol. 2014, Núm. 26, pp. 5720-5727
2013
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Michael additions in aqueous media: "on-water" and "in-water" processes from α-nitro ketones and their anions
European Journal of Organic Chemistry, pp. 1327-1336
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Synthesis of a d ring-functionalized derivative of the epiwelwistatin tetracyclic core
European Journal of Organic Chemistry, pp. 2802-2812
2012
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A one-pot sequence for the efficient synthesis of highly functionalized macrocarbocycles or bridged 2,8-dioxabicyclo[3.2.1]octanes from 1-nitrobicyclic compounds
Organic and Biomolecular Chemistry, Vol. 10, Núm. 26, pp. 5131-5136
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A systematic study of two complementary protocols allowing the general, mild and efficient deprotection of N-pivaloylindoles
Tetrahedron, Vol. 68, Núm. 2, pp. 705-710
2011
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A general, diastereoselective synthesis of highly functionalized bicyclo[n.3.1]alkane systems based on an anionic domino reaction of α-nitrocycloalkanones
European Journal of Organic Chemistry, pp. 2101-2110
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Domino reactions for the synthesis of bridged bicyclic frameworks: Fast access to bicyclo[n.3.1]alkanes
Chemical Society Reviews, Vol. 40, Núm. 7, pp. 3445-3454