MARÍA PILAR
HOYOS VIDAL
Profesora titular de universidad
ANDRÉS RAFAEL
ALCÁNTARA LEÓN
Catedrático de universidad
Publicaciones en las que colabora con ANDRÉS RAFAEL ALCÁNTARA LEÓN (27)
2021
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Structural insights into the desymmetrization of bulky 1,2-dicarbonyls through enzymatic monoreduction
Bioorganic Chemistry, Vol. 108
2019
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Biocatalyzed production of fine chemicals
Comprehensive Biotechnology (Elsevier), pp. 334-373
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Biocatalyzed synthesis of statins: A sustainable strategy for the preparation of valuable drugs
Catalysts, Vol. 9, Núm. 3
2018
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Merging lithium carbenoid homologation and enzymatic reduction: A combinative approach to the HIV-protease inhibitor Nelfinavir
Tetrahedron, Vol. 74, Núm. 18, pp. 2211-2217
2016
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Dynamic Kinetic Resolution via Hydrolase-Metal Combo Catalysis
Green Biocatalysis (wiley), pp. 373-396
2015
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Covalent Immobilization of Pseudomonas stutzeri Lipase on a Porous Polymer: An Efficient Biocatalyst for a Scalable Production of Enantiopure Benzoin Esters under Sustainable Conditions
Organic Process Research and Development, Vol. 19, Núm. 7, pp. 687-694
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First stereoselective acylation of a primary diol possessing a prochiral quaternary center mediated by lipase TL from Pseudomonas stutzeri
Tetrahedron, Vol. 71, Núm. 48, pp. 9172-9176
2014
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Chemoenzymatic synthesis of carbohydrates as antidiabetic and anticancer drugs
Current Topics in Medicinal Chemistry, Vol. 14, Núm. 23, pp. 2694-2711
2013
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Biocatalyzed on water synthesis of chiral building blocks for the preparation of anti-cancer drugs: A greener approach
Current Organic Chemistry, Vol. 17, Núm. 11, pp. 1132-1157
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Chemoselective CaO-mediated acylation of alcohols and amines in 2-methyltetrahydrofuran
ChemSusChem, Vol. 6, Núm. 5, pp. 905-910
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Lipase from Pseudomonas stutzeri: Purification, homology modelling and rational explanation of the substrate binding mode
Journal of Molecular Catalysis B: Enzymatic, Vol. 87, pp. 88-98
2012
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2-Methyltetrahydrofuran (2-MeTHF): A biomass-derived solvent with broad application in organic chemistry
ChemSusChem, Vol. 5, Núm. 8, pp. 1369-1379
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Dynamic kinetic resolution via hydrolase-metal combo catalysis in stereoselective synthesis of bioactive compounds
Advanced Synthesis and Catalysis, Vol. 354, Núm. 14-15, pp. 2585-2611
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Enantioselective reduction and deracemisation using the non-conventional yeast Pichia glucozyma in water/organic solvent biphasic systems: Preparation of (S)-1,2-diaryl-2-hydroxyethanones (benzoins)
Tetrahedron, Vol. 68, Núm. 2, pp. 523-528
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Industrial biotransformations in the synthesis of building blocks leading to enantiopure drugs
Bioresource Technology, Vol. 115, pp. 196-207
2011
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Chemoenzymatic synthesis of chiral unsymmetrical benzoin esters
Tetrahedron, Vol. 67, Núm. 38, pp. 7321-7329
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Highly regioselective and efficient synthesis of aminoepoxides by ring closure of aminohalohydrins mediated by KF-Celite
Synlett, pp. 1831-1834
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Optimised dynamic kinetic resolution of benzoin by a chemoenzymatic approach in 2-MeTHF
Journal of Molecular Catalysis B: Enzymatic, Vol. 72, Núm. 1-2, pp. 20-24
2010
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2-Methyltetrahydrofuran as a suitable green solvent for phthalimide functionalization promoted by supported KF
Green Chemistry, Vol. 12, Núm. 8, pp. 1380-1382
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Biocatalytic strategies for the asymmetric synthesis of α-hydroxy ketones
Accounts of Chemical Research, Vol. 43, Núm. 2, pp. 288-299