Publicaciones (74) Publicaciones de BEATRIZ DE LAS HERAS POLO

2023

  1. Labdane conjugates protect cardiomyocytes from doxorubicin-induced cardiotoxicity

    Drug Development Research, Vol. 84, Núm. 1, pp. 84-95

  2. Phenolic and quinone methide nor-triterpenes as selective NLRP3 inflammasome inhibitors

    Bioorganic Chemistry, Vol. 132

  3. Synthesis of Quinoline and Dihydroquinoline Embelin Derivatives as Cardioprotective Agents

    Journal of Natural Products, Vol. 86, Núm. 2, pp. 317-329

2022

  1. Dehydroisohispanolone as a Promising NLRP3 Inhibitor Agent: Bioevaluation and Molecular Docking

    Pharmaceuticals, Vol. 15, Núm. 7

  2. Terpenos: una nueva estrategia terapéutica en enfermedades inflamatorias mediadas por el inflamasoma NLRP3

    Anales de la Real Academia Nacional de Farmacia, Núm. 5, pp. 501-512

2021

  1. Productos naturales: de la medicina tradicional a cabezas de serie para el desarrollo de nuevos fármacos del siglo XXI.

    Anales de la Real Academia Nacional de Farmacia, Vol. 87, Núm. 1, pp. 97-104

  2. “Click & collect” para una rápida adaptación de la docencia práctica presencial a online en grados universitarios de Ciencias de la Salud

    Innovaciones docentes en tiempos de pandemia. Actas del VI congreso internacional sobre aprendizaje, innovación y cooperación, CINAIC 2021

2020

  1. Current status of terpenoids as inflammasome inhibitors

    Biochemical Pharmacology, Vol. 172

  2. Dehydrohispanolone Derivatives Attenuate the Inflammatory Response through the Modulation of Inflammasome Activation

    Journal of Natural Products, Vol. 83, Núm. 7, pp. 2155-2164

2019

  1. Amphiphilic acrylic nanoparticles containing the poloxamer star Bayfit®10WF15 as ophthalmic drug carriers

    Polymers, Vol. 11, Núm. 7

  2. Molecular targets involved in the neuroprotection mediated by terpenoids

    Planta Medica, Vol. 85, Núm. 17, pp. 1304-1315

  3. α-hispanolol induces apoptosis and suppresses migration and invasion of glioblastoma cells likely via downregulation of MMP-2/9 expression and p38MAPK attenuation

    Frontiers in Pharmacology, Vol. 10, Núm. JULY

2018

  1. A hispanolone-derived diterpenoid inhibits M2-Macrophage polarization in vitro via JAK/STAT and attenuates chitin induced inflammation in vivo

    Biochemical Pharmacology, Vol. 154, pp. 373-383

  2. GQ-11: A new PPAR agonist improves obesity-induced metabolic alterations in LDLr-/- mice

    International Journal of Obesity, Vol. 42, Núm. 5, pp. 1062-1072

  3. Semisynthesis and inhibitory effects of solidagenone derivatives on TLR-mediated inflammatory responses

    Molecules, Vol. 23, Núm. 12

2016

  1. New PPARγ partial agonist improves obesity-induced metabolic alterations and atherosclerosis in LDLr -/- mice

    Pharmacological Research, Vol. 104, pp. 49-60

  2. 8,9-Dehydrohispanolone-15,16-lactol diterpene prevents LPS-triggered inflammatory responses by inhibiting endothelial activation

    Biochemical Journal, Vol. 473, Núm. 14, pp. 2061-2071

  3. Novel water-soluble mucoadhesive carbosilane dendrimers for ocular administration

    Molecular Pharmaceutics, Vol. 13, Núm. 9, pp. 2966-2976

2015

  1. A labdane diterpene exerts ex vivo and in vivo cardioprotection against post-ischemic injury: Involvement of AKT-dependent mechanisms

    Biochemical Pharmacology, Vol. 93, Núm. 4, pp. 428-439

  2. Anti-inflammatory activity and phenolic profile of propolis from two locations in Región Metropolitana de Santiago, Chile

    Journal of Ethnopharmacology, Vol. 168, pp. 37-44