Publicaciones (30) Publicaciones de JOSÉ MANUEL GARCÍA SÁNCHEZ

2023

  1. Bisphenol-A Neurotoxic Effects on Basal Forebrain Cholinergic Neurons In Vitro and In Vivo

    Biology, Vol. 12, Núm. 6

  2. Cadmium-promoted thyroid hormones disruption mediates ROS, inflammation, Aβ and Tau proteins production, gliosis, spongiosis and neurodegeneration in rat basal forebrain

    Chemico-Biological Interactions, Vol. 375

2022

  1. Cadmium-induced neurotoxic effects on rat basal forebrain cholinergic system through thyroid hormones disruption

    Environmental Toxicology and Pharmacology, Vol. 90

  2. Insulin Signaling Disruption and INF-γUpregulation Induce Aβ1-42and Hyperphosphorylated-Tau Proteins Synthesis and Cell Death after Paraquat Treatment of Primary Hippocampal Cells

    Chemical Research in Toxicology, Vol. 35, Núm. 12, pp. 2214-2218

  3. Single and repeated bisphenol A treatment induces ROS, Aβ and hyperphosphorylated-tau accumulation, and insulin pathways disruption, through HDAC2 and PTP1B overexpression, leading to SN56 cholinergic apoptotic cell death

    Food and Chemical Toxicology, Vol. 170

2021

  1. Aryl Hydrocarbon Receptor Activation Produces Heat Shock Protein 90 and 70 Overexpression, Prostaglandin E2/Wnt/β-Catenin Signaling Disruption, and Cell Proliferation in MCF-7 and MDA-MB-231 Cells after 24 h and 14 Days of Chlorpyrifos Treatment

    Chemical Research in Toxicology, Vol. 34, Núm. 9, pp. 2019-2023

  2. Bisphenol A single and repeated treatment increases HDAC2, leading to cholinergic neurotransmission dysfunction and SN56 cholinergic apoptotic cell death through AChE variants overexpression and NGF/TrkA/P75NTR signaling disruption

    Food and Chemical Toxicology, Vol. 157

  3. Chlorpyrifos induces cell proliferation in MCF-7 and MDA-MB-231 cells, through cholinergic and Wnt/β-catenin signaling disruption, AChE-R upregulation and oxidative stress generation after single and repeated treatment

    Food and Chemical Toxicology, Vol. 152

  4. Paraquat Treatment Compromises the Clearance of β-Amyloid and Tau Proteins and Induces Primary Hippocampal Neuronal Cell Death through HSP70, P20S, and TFEB Disruption

    Chemical Research in Toxicology, Vol. 34, Núm. 5, pp. 1240-1244

2020

  1. Chlorpyrifos-induced cell proliferation in human breast cancer cell lines differentially mediated by estrogen and aryl hydrocarbon receptors and KIAA1363 enzyme after 24 h and 14 days exposure

    Chemosphere, Vol. 251

  2. Dysregulation of prostaglandine E2 and BDNF signaling mediated by estrogenic dysfunction induces primary hippocampal neuronal cell death after single and repeated paraquat treatment

    Food and Chemical Toxicology, Vol. 144

  3. Manganese increases Aβ and Tau protein levels through proteasome 20S and heat shock proteins 90 and 70 alteration, leading to SN56 cholinergic cell death following single and repeated treatment

    Ecotoxicology and Environmental Safety, Vol. 203

  4. Primary hippocampal estrogenic dysfunction induces synaptic proteins alteration and neuronal cell death after single and repeated paraquat exposure

    Food and Chemical Toxicology, Vol. 136

2019

  1. Manganese induced ROS and AChE variants alteration leads to SN56 basal forebrain cholinergic neuronal loss after acute and long-term treatment

    Food and Chemical Toxicology, Vol. 125, pp. 583-594

  2. Oxidative stress and cell death induction by amitraz and its metabolite BTS-27271 mediated through cytochrome P450 and NRF2 pathway alteration in primary hippocampal cell

    Food and Chemical Toxicology, Vol. 129, pp. 87-96

  3. Proteasome 20S and Rab5 Alteration after 24 h and 14 Days Chlorpyrifos Exposure Lead to β-Amyloid and Tau Protein Level Increases and SN56 Neuronal Cell Death

    Chemical Research in Toxicology, Vol. 32, Núm. 10, pp. 1920-1924

2018

  1. Cadmium alters heat shock protein pathways in SN56 cholinergic neurons, leading to Aβ and phosphorylated Tau protein generation and cell death

    Food and Chemical Toxicology, Vol. 121, pp. 297-308

  2. SN56 neuronal cell death after 24 h and 14 days chlorpyrifos exposure through glutamate transmission dysfunction, increase of GSK-3β enzyme, β-amyloid and tau protein levels

    Toxicology, Vol. 402-403, pp. 17-27

2017

  1. Amitraz changes NE, DA and 5-HT biosynthesis and metabolism mediated by alterations in estradiol content in CNS of male rats

    Chemosphere, Vol. 181, pp. 518-529

  2. Effects of sex hormones disruption, after prenatal and postnatal exposure to chlordimeform, on monoaminergic neurotransmitters systems in female and male rat’s prefrontal cortex

    Medicina balear, Vol. 32, Núm. 1, pp. 11-19