Publications (195) Publications de GUSTAVO BARJA DE QUIROGA LOSADA

2023

  1. Introduction to special issue on ‘physiological and evolutionary mechanisms of aging’

    Experimental Gerontology

  2. Mitochondrial ROS production, oxidative stress and aging within and between species: Evidences and recent advances on this aging effector

    Experimental Gerontology, Vol. 174

  3. Phenotypic molecular features of long-lived animal species

    Free Radical Biology and Medicine, Vol. 208, pp. 728-747

  4. Programmed versus non-programmed evolution of aging. What is the evidence?

    Experimental Gerontology, Vol. 175

  5. Whole organism aging: Parabiosis, inflammaging, epigenetics, and peripheral and central aging clocks. The ARS of aging

    Experimental Gerontology, Vol. 174

2022

  1. Elovl2-Ablation Leads to Mitochondrial Membrane Fatty Acid Remodeling and Reduced Efficiency in Mouse Liver Mitochondria

    Nutrients, Vol. 14, Núm. 3

  2. Methionine Metabolism Is Down-Regulated in Heart of Long-Lived Mammals

    Biology, Vol. 11, Núm. 12

2021

  1. Higher DNA repair in mitoc h o ndr i a of lo n g-lived species

    Aging, Vol. 13, Núm. 18, pp. 21808-21809

  2. Is the NDUFV2 subunit of the hydrophilic complex I domain a key determinant of animal longevity?

    FEBS Journal

  3. mTORC1 is also involved in longevity between species

    Aging

2020

  1. Gene expression and regulatory factors of the mechanistic target of rapamycin (mTOR) complex 1 predict mammalian longevity

    GeroScience, Vol. 42, Núm. 4, pp. 1157-1173

  2. Low abundance of NDUFV2 and NDUFS4 subunits of the hydrophilic complex I domain and VDAC1 predicts mammalian longevity

    Redox Biology, Vol. 34

  3. Membrane peroxidation index and maximum lifespan are negatively correlated in fish of the genus Nothobranchius

    The Journal of experimental biology, Vol. 223

  4. Mitochondrial base excision repair positively correlates with longevity in the liver and heart of mammals

    GeroScience, Vol. 42, Núm. 2, pp. 653-665

2019

  1. Towards a unified mechanistic theory of aging

    Experimental Gerontology, Vol. 124

2017

  1. Increase in mitochondrial DNA fragments inside nuclear DNA during the lifetime of an individual as a mechanism of aging

    Aging: Exploring a Complex Phenomenon (CRC Press), pp. 383-394

  2. Mitochondrial ROS and mtDNA fragments inside nuclear DNA as a main effector of ageing: the "cell aging regulation system”

    Anales de la Real Academia Nacional de Farmacia, Vol. 83, Núm. 1, pp. 48-80

2016

  1. Rapamycin reverses age-related increases in mitochondrial ROS production at complex I, oxidative stress, accumulation of mtDNA fragments inside nuclear DNA, and lipofuscin level, and increases autophagy, in the liver of middle-aged mice

    Experimental Gerontology, Vol. 83, pp. 130-138

  2. Reduced apurinic/apyrimidinic endonuclease 1 activity and increased DNA damage in mitochondria are related to enhanced apoptosis and inflammation in the brain of senescence- accelerated P8 mice (SAMP8)

    Biogerontology, Vol. 17, Núm. 2, pp. 325-335

2015

  1. Cysteine dietary supplementation reverses the decrease in mitochondrial ROS production at complex I induced by methionine restriction

    Journal of Bioenergetics and Biomembranes, Vol. 47, Núm. 3, pp. 199-208