JOSÉ LUIS
MARCO CONTELLES
Researcher in the period 2018-2019
![Foto de JOSÉ LUIS](/img/nophoto.png)
![Foto de Universidade de Lisboa](/img/noimage_org.png)
Universidade de Lisboa
Lisboa, PortugalPublications in collaboration with researchers from Universidade de Lisboa (32)
2021
-
Five-Membered-Ring-Fused Tacrines as Anti-Alzheimer's Disease Agents
Synlett, Vol. 32, Núm. 20, pp. 1987-2012
-
Synthesis and Fluorescence of (E)-3-Aryl-2-(5-aryl-4H-1,2,4-triazol-3-yl) Acrylonitriles
ChemistrySelect, Vol. 6, Núm. 25, pp. 6360-6364
2020
-
Propargylamine-derived multi-target directed ligands for Alzheimer's disease therapy
Bioorganic and Medicinal Chemistry Letters, Vol. 30, Núm. 3
-
Synthesis, biological evaluation, and molecular modeling of nitrile-containing compounds: Exploring multiple activities as anti-Alzheimer agents
Drug Development Research, Vol. 81, Núm. 2, pp. 215-231
2019
-
Synthesis and biological assessment of KojoTacrines as new agents for Alzheimer’s disease therapy
Journal of Enzyme Inhibition and Medicinal Chemistry, Vol. 34, Núm. 1, pp. 163-170
2017
-
Multitarget-Directed Antioxidants as Therapeutic Agents: Putting the Focus on the Oxidative Stress
Design of Hybrid Molecules for Drug Development (Elsevier Inc.), pp. 5-46
2016
-
ASS234, as a new multi-target directed propargylamine for Alzheimer's disease therapy
Frontiers in Neuroscience, Vol. 10, Núm. JUN
2015
-
Predicting targets of compounds against neurological diseases using cheminformatic methodology
Journal of Computer-Aided Molecular Design, Vol. 29, Núm. 2, pp. 183-198
2014
-
Exploring the structural basis of the selective inhibition of monoamine oxidase A by dicarbonitrile aminoheterocycles: Role of Asn181 and Ile335 validated by spectroscopic and computational studies
Biochimica et Biophysica Acta - Proteins and Proteomics, Vol. 1844, Núm. 2, pp. 389-397
2013
-
Multipotent 1,8-naphthyridines, as new tacrine analogues, for the treatment of Alzheimer's disease
Bioactive Heterocycles: Synthesis and Biological Evaluation (Nova Science Publishers, Inc.), pp. 1-18
-
Synthesis, pharmacological assessment, and molecular modeling of acetylcholinesterase/butyrylcholinesterase inhibitors: Effect against amyloid-β-induced neurotoxicity
ACS Chemical Neuroscience, Vol. 4, Núm. 4, pp. 547-565
-
The multifactorial nature of Alzheimer's disease for developing potential therapeutics
Current Topics in Medicinal Chemistry, Vol. 13, Núm. 15, pp. 1745-1770
2011
-
A practical two-step synthesis of imidazo[1,2-a]pyridines from N-(prop-2-yn-1-yl)pyridin-2-amines
Chemical Communications, Vol. 47, Núm. 17, pp. 5043-5045
-
Microwave irradiation-assisted amination of 2-chloropyridine derivatives with amide solvents
Synthetic Communications, Vol. 41, Núm. 19, pp. 2859-2869
-
Synthesis and biological assessment of diversely substituted furo[2,3-b]quinolin-4-amine and pyrrolo[2,3-b]quinolin-4-amine derivatives, as novel tacrine analogues
European Journal of Medicinal Chemistry, Vol. 46, Núm. 12, pp. 6119-6130
-
Synthesis and pharmacological assessment of diversely substituted pyrazolo[3,4-b]quinoline, and benzo[b]pyrazolo[4,3-g][1,8]naphthyridine derivatives
European Journal of Medicinal Chemistry, Vol. 46, Núm. 9, pp. 4676-4681
2010
-
Synthesis of (E)-diethyl 6,6′-(diazene-1,2-diyl)bis(5-cyano-2-methyl- 4-phenylnicotinates), a new type of 2,2′-azopyridine dyes
Tetrahedron Letters, Vol. 51, Núm. 48, pp. 6278-6281
-
Synthesis of new 7-azabicyclo[2.2.1]heptane derivatives
Arkivoc, Vol. 2010, Núm. 3, pp. 56-73
-
The multifactorial nature of alzheimer's disease and related therapeutic strategies
Current Pharmaceutical Design
-
The sandmeyer reaction on some selected heterocyclic ring systems: Synthesis of useful 2-chloroheterocyclic-3-carbonitrile intermediates
Synthesis, pp. 2725-2730