Publications en collaboration avec des chercheurs de Universidade de Lisboa (32)

2021

  1. Five-Membered-Ring-Fused Tacrines as Anti-Alzheimer's Disease Agents

    Synlett, Vol. 32, Núm. 20, pp. 1987-2012

  2. Synthesis and Fluorescence of (E)-3-Aryl-2-(5-aryl-4H-1,2,4-triazol-3-yl) Acrylonitriles

    ChemistrySelect, Vol. 6, Núm. 25, pp. 6360-6364

2020

  1. Propargylamine-derived multi-target directed ligands for Alzheimer's disease therapy

    Bioorganic and Medicinal Chemistry Letters, Vol. 30, Núm. 3

  2. Synthesis, biological evaluation, and molecular modeling of nitrile-containing compounds: Exploring multiple activities as anti-Alzheimer agents

    Drug Development Research, Vol. 81, Núm. 2, pp. 215-231

2019

  1. Synthesis and biological assessment of KojoTacrines as new agents for Alzheimer’s disease therapy

    Journal of Enzyme Inhibition and Medicinal Chemistry, Vol. 34, Núm. 1, pp. 163-170

2017

  1. Multitarget-Directed Antioxidants as Therapeutic Agents: Putting the Focus on the Oxidative Stress

    Design of Hybrid Molecules for Drug Development (Elsevier Inc.), pp. 5-46

2016

  1. ASS234, as a new multi-target directed propargylamine for Alzheimer's disease therapy

    Frontiers in Neuroscience, Vol. 10, Núm. JUN

2015

  1. Predicting targets of compounds against neurological diseases using cheminformatic methodology

    Journal of Computer-Aided Molecular Design, Vol. 29, Núm. 2, pp. 183-198

2014

  1. Exploring the structural basis of the selective inhibition of monoamine oxidase A by dicarbonitrile aminoheterocycles: Role of Asn181 and Ile335 validated by spectroscopic and computational studies

    Biochimica et Biophysica Acta - Proteins and Proteomics, Vol. 1844, Núm. 2, pp. 389-397

2013

  1. Multipotent 1,8-naphthyridines, as new tacrine analogues, for the treatment of Alzheimer's disease

    Bioactive Heterocycles: Synthesis and Biological Evaluation (Nova Science Publishers, Inc.), pp. 1-18

  2. Synthesis, pharmacological assessment, and molecular modeling of acetylcholinesterase/butyrylcholinesterase inhibitors: Effect against amyloid-β-induced neurotoxicity

    ACS Chemical Neuroscience, Vol. 4, Núm. 4, pp. 547-565

  3. The multifactorial nature of Alzheimer's disease for developing potential therapeutics

    Current Topics in Medicinal Chemistry, Vol. 13, Núm. 15, pp. 1745-1770

2011

  1. A practical two-step synthesis of imidazo[1,2-a]pyridines from N-(prop-2-yn-1-yl)pyridin-2-amines

    Chemical Communications, Vol. 47, Núm. 17, pp. 5043-5045

  2. Microwave irradiation-assisted amination of 2-chloropyridine derivatives with amide solvents

    Synthetic Communications, Vol. 41, Núm. 19, pp. 2859-2869

  3. Synthesis and biological assessment of diversely substituted furo[2,3-b]quinolin-4-amine and pyrrolo[2,3-b]quinolin-4-amine derivatives, as novel tacrine analogues

    European Journal of Medicinal Chemistry, Vol. 46, Núm. 12, pp. 6119-6130

  4. Synthesis and pharmacological assessment of diversely substituted pyrazolo[3,4-b]quinoline, and benzo[b]pyrazolo[4,3-g][1,8]naphthyridine derivatives

    European Journal of Medicinal Chemistry, Vol. 46, Núm. 9, pp. 4676-4681

2010

  1. Synthesis of (E)-diethyl 6,6′-(diazene-1,2-diyl)bis(5-cyano-2-methyl- 4-phenylnicotinates), a new type of 2,2′-azopyridine dyes

    Tetrahedron Letters, Vol. 51, Núm. 48, pp. 6278-6281

  2. Synthesis of new 7-azabicyclo[2.2.1]heptane derivatives

    Arkivoc, Vol. 2010, Núm. 3, pp. 56-73

  3. The multifactorial nature of alzheimer's disease and related therapeutic strategies

    Current Pharmaceutical Design

  4. The sandmeyer reaction on some selected heterocyclic ring systems: Synthesis of useful 2-chloroheterocyclic-3-carbonitrile intermediates

    Synthesis, pp. 2725-2730