Instituto Universitario de Investigación en Neuroquímica
Centro/Instituto
J.
Egea
Publicaciones en las que colabora con J. Egea (28)
2024
2021
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Analogues of cannabinoids as multitarget drugs in the treatment of Alzheimer's disease
European Journal of Pharmacology, Vol. 895
2020
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Na+ controls hypoxic signalling by the mitochondrial respiratory chain
Nature, Vol. 586, Núm. 7828, pp. 287-291
2018
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Folic Acid Protects Against Glutamate-Induced Excitotoxicity in Hippocampal Slices Through a Mechanism that Implicates Inhibition of GSK-3β and iNOS
Molecular Neurobiology, Vol. 55, Núm. 2, pp. 1580-1589
2017
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ConBr, A Lectin Purified from the Seeds of Canavalia brasiliensis, Protects Against Ischemia in Organotypic Culture of Rat Hippocampus: Potential Implication of Voltage-Gated Calcium Channels
Neurochemical Research, Vol. 42, Núm. 2, pp. 347-359
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Mitochondrial complex I deactivation is related to superoxide production in acute hypoxia
Redox Biology, Vol. 12, pp. 1040-1051
2016
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Agmatine, by Improving Neuroplasticity Markers and Inducing Nrf2, Prevents Corticosterone-Induced Depressive-Like Behavior in Mice
Molecular Neurobiology, Vol. 53, Núm. 5, pp. 3030-3045
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Nrf2-ARE pathway: An emerging target against oxidative stress and neuroinflammation in neurodegenerative diseases
Pharmacology and Therapeutics, Vol. 157, pp. 84-104
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Subthreshold Concentrations of Melatonin and Galantamine Improves Pathological AD-Hallmarks in Hippocampal Organotypic Cultures
Molecular Neurobiology, Vol. 53, Núm. 5, pp. 3338-3348
2015
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Agmatine Induces Nrf2 and Protects Against Corticosterone Effects in Hippocampal Neuronal Cell Line
Molecular Neurobiology, Vol. 51, Núm. 3, pp. 1504-1519
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Alpha7 nicotinic receptor activation protects against oxidative stress via heme-oxygenase i induction
Biochemical Pharmacology, Vol. 97, Núm. 4, pp. 473-481
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Anti-inflammatory role of microglial alpha7 nAChRs and its role in neuroprotection
Biochemical Pharmacology, Vol. 97, Núm. 4, pp. 463-472
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Both creatine and its product phosphocreatine reduce oxidative stress and afford neuroprotection in an in vitro Parkinson’s model
ASN Neuro, Vol. 6, Núm. 6
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Melatonin-sulforaphane hybrid ITH12674 induces neuroprotection in oxidative stress conditions by a 'drug-prodrug' mechanism of action
British Journal of Pharmacology, Vol. 172, Núm. 7, pp. 1807-1821
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Microglial HO-1 induction by curcumin provides antioxidant, antineuroinflammatory, and glioprotective effects
Molecular Nutrition and Food Research, Vol. 59, Núm. 9, pp. 1690-1700
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New melatonin-cinnamate hybrids as multi-target drugs for neurodegenerative diseases: Nrf2-induction, antioxidant effect and neuroprotection
Future Medicinal Chemistry, Vol. 7, Núm. 15, pp. 1961-1969
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Positive allosteric modulation of alpha-7 nicotinic receptors promotes cell death by inducing Ca2+ release from the endoplasmic reticulum
Journal of Neurochemistry, Vol. 133, Núm. 3, pp. 309-319
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The melatonin- N,N-dibenzyl(N-methyl)amine hybrid ITH91/IQM157 affords neuroprotection in an in vitro Alzheimer's model via hemo-oxygenase-1 induction
ACS Chemical Neuroscience, Vol. 6, Núm. 2, pp. 288-296
2014
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ITH12410/SC058: A new neuroprotective compound with potential in the treatment of Alzheimer's disease
ACS Chemical Neuroscience, Vol. 5, Núm. 9, pp. 770-775