Ciencias Biológicas
Faculté
GUSTAVO
BARJA DE QUIROGA LOSADA
Chercheur jusqu' 2020
Publications dans lesquelles il/elle collabore avec GUSTAVO BARJA DE QUIROGA LOSADA (196)
2023
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Introduction to special issue on ‘physiological and evolutionary mechanisms of aging’
Experimental Gerontology
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Mitochondrial ROS production, oxidative stress and aging within and between species: Evidences and recent advances on this aging effector
Experimental Gerontology, Vol. 174
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Phenotypic molecular features of long-lived animal species
Free Radical Biology and Medicine, Vol. 208, pp. 728-747
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Programmed versus non-programmed evolution of aging. What is the evidence?
Experimental Gerontology, Vol. 175
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Whole organism aging: Parabiosis, inflammaging, epigenetics, and peripheral and central aging clocks. The ARS of aging
Experimental Gerontology, Vol. 174
2022
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Elovl2-Ablation Leads to Mitochondrial Membrane Fatty Acid Remodeling and Reduced Efficiency in Mouse Liver Mitochondria
Nutrients, Vol. 14, Núm. 3
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Methionine Metabolism Is Down-Regulated in Heart of Long-Lived Mammals
Biology, Vol. 11, Núm. 12
2021
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Higher DNA repair in mitoc h o ndr i a of lo n g-lived species
Aging, Vol. 13, Núm. 18, pp. 21808-21809
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Is the NDUFV2 subunit of the hydrophilic complex I domain a key determinant of animal longevity?
FEBS Journal
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mTORC1 is also involved in longevity between species
Aging
2020
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Gene expression and regulatory factors of the mechanistic target of rapamycin (mTOR) complex 1 predict mammalian longevity
GeroScience, Vol. 42, Núm. 4, pp. 1157-1173
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Low abundance of NDUFV2 and NDUFS4 subunits of the hydrophilic complex I domain and VDAC1 predicts mammalian longevity
Redox Biology, Vol. 34
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Membrane peroxidation index and maximum lifespan are negatively correlated in fish of the genus Nothobranchius
The Journal of experimental biology, Vol. 223
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Mitochondrial base excision repair positively correlates with longevity in the liver and heart of mammals
GeroScience, Vol. 42, Núm. 2, pp. 653-665
2019
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Towards a unified mechanistic theory of aging
Experimental Gerontology, Vol. 124
2017
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Increase in mitochondrial DNA fragments inside nuclear DNA during the lifetime of an individual as a mechanism of aging
Aging: Exploring a Complex Phenomenon (CRC Press), pp. 383-394
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Mitochondrial ROS and mtDNA fragments inside nuclear DNA as a main effector of ageing: the "cell aging regulation system”
Anales de la Real Academia Nacional de Farmacia, Vol. 83, Núm. 1, pp. 48-80
2016
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Rapamycin reverses age-related increases in mitochondrial ROS production at complex I, oxidative stress, accumulation of mtDNA fragments inside nuclear DNA, and lipofuscin level, and increases autophagy, in the liver of middle-aged mice
Experimental Gerontology, Vol. 83, pp. 130-138
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Reduced apurinic/apyrimidinic endonuclease 1 activity and increased DNA damage in mitochondria are related to enhanced apoptosis and inflammation in the brain of senescence- accelerated P8 mice (SAMP8)
Biogerontology, Vol. 17, Núm. 2, pp. 325-335
2015
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Cysteine dietary supplementation reverses the decrease in mitochondrial ROS production at complex I induced by methionine restriction
Journal of Bioenergetics and Biomembranes, Vol. 47, Núm. 3, pp. 199-208