Virulencia de aislados de Leishmania infantum procedentes del brote de leishmaniosis humana en la Comunidad de Madridcaracterización y evaluación en células de reservorios mamíferos

  1. Alicia Mas Zubiri
Supervised by:
  1. Francisco Javier Carrión Herrero Director
  2. Gustavo Domínguez Bernal Director

Defence university: Universidad Complutense de Madrid

Year of defence: 2021

  1. A. Sainz Chair
  2. Ana Montoya Matute Secretary
  3. Juan Fernando Alzate Restrepo Committee member
  4. José Julio Martín Plaza Committee member
  5. Christopher Fernández Prada Committee member
  1. Sanidad Animal

Type: Thesis


Zoonotic visceral leishmaniasis (ZVL) caused by L. infantum is a parasitic disease that constitutes a major public health challenge as it affects both humans and dogs, the main reservoir. The transmission is carried by insects called phlebotomine sandflies belonging to the genus Lutzomyia in Central and South America and Phlebotomus in the Mediterranean Basin, the Middle East and Asia. It is a disease that causes a wide spectrum of clinical presentations, with both cutaneous and visceral manifestations, which can even lead to death if not adequately treated...