Estudio TRANSFAIR en España. III. Asociación entre el depósito en tejido adiposo de isómeros de ácidos grasos cis y trans con la ingesta y fracciones lipídicas plasmáticas 327
- C. Cuadrado 1
- A. Carbajal 1
- C. Núñez 1
- B. Beltrán 1
- G. Toledano 1
- O. Moreiras 1
- 1 Departamento de Nutrición. Facultad de Farmacia. Universidad Complutense de Madrid
ISSN: 0214-9168, 1578-1879
Ano de publicación: 2000
Volume: 12
Número: 6
Páxinas: 327-332
Tipo: Artigo
Outras publicacións en: Clínica e investigación en arteriosclerosis
Resumo
Background. High intakes of trans fatty acids (TFA) have been found to exert undesirable effects on serum lipid profiles, and thus may increase the risk of cardiovascular disease. Design. Cross-sectional study with participation of 37 men and 47 women who were selected from a housekeeper association and two industries from Segovia (Spain), aged 50 to 65 years. Using a dietary history method, food consumption was assessed and TFA intake was calculated with recent figures on TFA content of food collected in the TRANSFAIR study. The fatty acid (C:12 to C:22) composition of adipose tissue from biopsies was measured by gas chromatography of subcutaneous fat. Results. Mean (± SD) TFA intake was 1.40 ± 0.64 g/day for men and 1.75 ± 0.74 g/day for women. The most abundantly occurring TFA isomer in adipose tissue was C18:1*9 (47.35 ± 5.03 g for men and 51.42 ± 3.23 g for women) followed by palmitic acid and linoleic acid. Significative association for men and women was observed between the intake of C18:1 T and HDL-cholesterol (r = 0.31; p < 0.01) and for women (r = 0.50; p < 0.001), and for all the sample, between TFA intake and HDL-cholesterol (r = 0.29; p < 0.01) and for women (r = 0.48; p < 0.001). Conclusions. From this study we conclude that at the current Spain intake levels of trans fatty acids they are not associated with an unfavourable serum lipid profile.