Papel de p21/CDKN1A en la enfermedad hepática crónicaRole of p21/CDKN1A in chronic liver disease (CLD)

  1. LAMAS PAZ, ARANTZA
Zuzendaria:
  1. Yulia Nevzorova Zuzendaria
  2. Francisco Javier Cubero Palero Zuzendaria

Defentsa unibertsitatea: Universidad Complutense de Madrid

Fecha de defensa: 2022(e)ko uztaila-(a)k 06

Epaimahaia:
  1. Salvador Iborra Martín Presidentea
  2. Ana Victoria Marín Marín Idazkaria
  3. Jordi García Kidea
  4. Gonzalo Jorquero Olave Kidea
  5. Rocío Gallego Durán Kidea

Mota: Tesia

Teseo: 811014 DIALNET lock_openDocta Complutense editor

Laburpena

The increasing incidence of obesity and non-alcoholic fatty liver disease(NAFLD/NASH) currently represents a serious threat to global health, potentially leadingto an increase in the number of cases of advanced liver disease, cirrhosis and, ultimately,leading to hepatocellular carcinoma (HCC). The p21/CDKN1A gene is a cell cycleregulator that is involved in essential cellular processes such as: cell cycle arrest,apoptosis, differentiation, senescence, and DNA repair. The main aim of this study wasto evaluate the specific role of p21/CDKN1A in chronic liver disease (CLD)...