Papel de p21/CDKN1A en la enfermedad hepática crónicaRole of p21/CDKN1A in chronic liver disease (CLD)

  1. LAMAS PAZ, ARANTZA
Dirixida por:
  1. Yulia Nevzorova Director
  2. Francisco Javier Cubero Palero Director

Universidade de defensa: Universidad Complutense de Madrid

Fecha de defensa: 06 de xullo de 2022

Tribunal:
  1. Salvador Iborra Martín Presidente
  2. Ana Victoria Marín Marín Secretaria
  3. Jordi García Vogal
  4. Gonzalo Jorquero Olave Vogal
  5. Rocío Gallego Durán Vogal

Tipo: Tese

Teseo: 811014 DIALNET lock_openDocta Complutense editor

Resumo

The increasing incidence of obesity and non-alcoholic fatty liver disease(NAFLD/NASH) currently represents a serious threat to global health, potentially leadingto an increase in the number of cases of advanced liver disease, cirrhosis and, ultimately,leading to hepatocellular carcinoma (HCC). The p21/CDKN1A gene is a cell cycleregulator that is involved in essential cellular processes such as: cell cycle arrest,apoptosis, differentiation, senescence, and DNA repair. The main aim of this study wasto evaluate the specific role of p21/CDKN1A in chronic liver disease (CLD)...